Faculty Profile

Muralidhar Padala, PhD

Muralidhar Padala, PhD

Associate Professor, Division of Cardiothoracic Surgery, Emory University

Director, Structural Heart Research & Innovation Program, Cardiothoracic Research Laboratories, Carlyle Fraser Heart Center at Emory University Hospital Midtown

Graduate Program Faculty, Department of Biomedical Engineering, Georgia Institute of Technology

Institute Faculty, Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology

Telephone: 404.251.0651

Email: spadala@emory.edu

Year Joined Emory as a Faculty Member: 2010

Biography

Dr. Padala is a tenured associate professor of cardiothoracic surgery and director of the structural heart research and innovation laboratory in the Division of Cardiothoracic Surgery. His research interests involve the development of new surgical techniques and surgical and interventional devices and implants for cardiac surgical applications, and investigations of their effect on cardiac tissue remodeling and adaptation.

His current research projects are focused on three areas:

  1. Mechanics and mechanobiology of valvular heart disease, with a concentration on developing surgical techniques and interventions that restore physiological valve biomechanics for long term durability.
  2. Heart failure therapies, particularly surgical techniques and devices to unload the failing heart and trigger reparative signaling.
  3. Developing new surgical approaches, biomaterials, and devices for children with congenital heart defects.

Dr. Padala received his BS in Mechanical Engineering in 2004, a PhD in Bioengineering from the Georgia Institute of Technology in 2010, and completed a research fellowship at Imperial College London in 2012. His research lab is currently funded by multiple R01 grants from the NHLBI, training grants from the American Heart Association, industry projects, and infrastructure support from the Carlyle Fraser Heart Center at Emory University Hospital Midtown.

Visit Dr. Padala's website for his Structural Heart Research and Innovation Lab.

Publications

View Dr. Padala's publications in PubMed.

Affiliations

  • Carlyle Fraser Heart Center at Emory University Hospital Midtown

  • Institute Faculty, Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology

Education

  • Research Fellowship, Imperial College London, 2012

  • PhD in Bioengineering, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 2010

  • MS in Mechanical Engineering, Georgia Institute of Technology, 2008

  • BS in Mechanical Engineering, Osmania University, India, 2004

Honors and Awards

  • Innovation for Impact Award, Emory University School of Medicine, 2019

  • Albert E. Levy Scientific Research Award, Emory University Office of the Provost, 2018

  • Subramanian Innovation Award, International Society of Minimally Invasive Cardiothoracic Surgery (ISMICS), 2017

  • William Parmley Prize, American College of Cardiology, 2015

  • American Heart Association Scientist Development Award, 2014

  • Leducq Foundation Career Development Award, 2012

  • Emory University Innovation of the Year Award, 2011

  • Gandy Diaz Teaching Fellowship, Georgia Institute of Technology, 2009

  • American Heart Association Pre-Doctoral Fellowship, 2008

Current Organizational Memberships

  • American Heart Association

  • Biomedical Engineering Society

  • Heart Valve Society

Editorships and Editorial Boards

  • Editorial Board, Journal of Thoracic and Cardiovascular Surgery, 2017-present

  • Editorial Board, Journal of Heart Valve Disease, 2018-present

  • Associate Editor, BMC Cardiovascular Disorders, 2018-present

Basic Science Research Interests

  • Heart valve tissue mechanics and remodeling to surgical repairs

  • Cardiac chamber remodeling to abnormal hemodynamic stress

  • Blood flow dynamics in congenital heart lesions

Clinical Research Interests

  • Longitudinal studies of cardiovascular biomechanics in post-cardiac surgery patients using imaging

  • Quantitative tissue remodeling studies using human tissue biorepositories

Translational Research Interests

  • Image guided interventions for structural heart lesions

  • Cardiac unloading devices for heart failure

  • Biomaterials with growth potential