Faculty Profile

Muralidhar Padala, PhD

Muralidhar Padala, PhD

Assistant Professor, Division of Cardiothoracic Surgery, Emory University

Director, Structural Heart Research & Innovation Program, Cardiothoracic Research Laboratories, Carlyle Fraser Heart Center at Emory University Hospital Midtown

Adjunct Assistant Professor, Department of Biomedical Engineering, Georgia Institute of Technology

Institute Faculty, Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology

Telephone: 404.251.0651

Email: spadala@emory.edu

Year Joined Emory as a Faculty Member: 2010

Biography

Dr. Padala is an assistant professor of cardiothoracic surgery and director of the structural heart research and innovation laboratory in the Division of Cardiothoracic Surgery. Through the use of novel animal models to manipulate mechanical forces, his research focuses on the mechanobiologic signaling in heart valve disease, heart failure, and atherosclerosis. With this methodology, his lab has developed new devices that can alter the disease state or tissue adaptation to these mechanical forces.

Dr. Padala received his PhD in Bioengineering in 2010 from the Georgia Institute of Technology—his thesis focused on heart valve mechanics after surgical repair with different techniques. He completed a research fellowship at Imperial College London that studied the interaction between mechanics and genetic mutations in valve tissue. His current interdisciplinary research team consists of surgeons, bioengineers, molecular biologists, and veterinarians, and is funded by grants from the NIH, American Heart Association, Coulter Foundation, Georgia Research Alliance, and industry.

Visit Dr. Padala's website for his Structural Heart Research and Innovation Lab.

Publications

View Dr. Padala's publications in PubMed.

Affiliations

  • Carlyle Fraser Heart Center at Emory University Hospital Midtown

  • Institute Faculty, Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology

Education

  • Research Fellowship, Imperial College London, 2012

  • PhD in Bioengineering, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 2010

  • MS in Mechanical Engineering, Georgia Institute of Technology, 2008

  • BS in Mechanical Engineering, Osmania University, India, 2004

Honors and Awards

  • Subramanian Innovation Award, International Society of Minimally Invasive Cardiothoracic Surgery (ISMICS), 2017

  • William Parmley Prize, American College of Cardiology, 2015

  • American Heart Association Scientist Development Award, 2014

  • Leducq Foundation Career Development Award, 2012

  • Emory University Innovation of the Year Award, 2011

  • Gandy Diaz Teaching Fellowship, Georgia Institute of Technology, 2009

  • American Heart Association Pre-Doctoral Fellowship, 2008

Current Organizational Memberships

  • American Heart Association

  • Biomedical Engineering Society

  • Heart Valve Society

Editorships and Editorial Boards

  • Editorial Board, Journal of Thoracic and Cardiovascular Surgery, 2017–present

Basic Science Research Interests

  • Cardiovascular tissue adaptation to abnormal mechanical forces

  • Mechanobiology of heart valve disease, heart failure, and atherosclerosis

  • Multi-scale (organ, tissue, matrix, cell, genome) changes in cardiovascular tissue adapting to altered mechanics (from injury or after surgical repair)

Clinical Research Interests

  • Clinical imaging derived cardiac biomechanical analysis in patients

  • Biomarkers to map tissue remodeling to adverse mechanical loading

Translational Research Interests

  • Translating biomechanically optimal surgical techniques from lab to the patient

  • Transcatheter heart valve interventions

  • New mechanosensitive and responsive biomaterials